antimicrobial susceptibility pattern of staphylococcus aureus strains isolated from hospitalized patients in tehran, iran
نویسندگان
چکیده
staphylococcus aureus is a major bacterial pathogen that causes different community- and hospital-acquired infections. over time, strains of s. aureus have become resistant to different antibiotics including penicillinase-resistant penicillins. having data on the local antimicrobial susceptibility pattern of this pathogen is necessary for selection of appropriate antibiotics for empirical treatment of infections due to it. to determine the antimicrobial susceptibility pattern of staphylococcus aureus strains isolated from hospitalized patients in tehran, iran, in a prospective cross-sectional study performed at imam khomeini hospital, samples were collected from hospitalized patients and were cultured. all positive cultures which yielded s. aureus underwent antimicrobial susceptibility testing using the kirby-bauer disk diffusion method on mueller-hinton agar. the results were interpreted after 24 hours of incubation at 37 °c. a total of 160 clinical isolates of s. aureus were collected. most isolates were obtained from blood (29%). the overall susceptibility of isolated s. aureus strains to antimicrobial agents was 100% for vancomycin, 49.4% for amikacin, 43.8% for gentamicin, 36.8% for co-trimoxazole and tetracycline, 36.3% for cefazolin, 30.6% for cephalexin, 24.4% for oxacillin, 23.8% for erythromycin, and 3.1% for penicillin. other than vancomycin, none of the tested antibiotics are appropriate for empirical treatment of serious s .aureus infections in our area.
منابع مشابه
Antimicrobial Susceptibility Pattern of Staphylococcus aureus Strains Isolated from Hospitalized Patients in Tehran, Iran
Staphylococcus aureus is a major bacterial pathogen that causes different community- and hospital-acquired infections. Over time, strains of S. aureus have become resistant to different antibiotics including penicillinase-resistant penicillins. Having data on the local antimicrobial susceptibility pattern of this pathogen is necessary for selection of appropriate...
متن کاملSusceptibility To Vancomycin In Staphylococcus Aureus Isolated From Patients Of Four University-Affiliated Hospitals In Tehran
Background and Objective: Vancomycin is frequently the antibiotic of choice for the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA). For the last years, the incidence of vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA) has been increased in various parts of the world. The present study ...
متن کاملInvestigating antibacterial activity of Satureja bachtiarica against coagulasenegative staphylococcus strains isolated from hospitalized patients in ICU,Tehran-Iran
Given the inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. Satureja bachtiaricais a medicinal plant which had many uses in traditional medicine. In this research, the ethanolextract of leave of Satureja bachtiarica is tested on coagulase-negative staphylococcus strains.Materials and ...
متن کاملAntibiotic Susceptibility of Staphylococcus aureus and Enterococcus Spp. Isolated from some Hospitals in Tehran
Abstract Background and Objective: Vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) are the leading nosocomial pathogens in Iran. We aimed at evaluating the resistance patterns of Staphylococcus aureus and enterococci to the antibiotics recommended by Clinical and Laboratory Standards Institute (CLSI). Material and Methods: Two-hu...
متن کاملAntibiotic Susceptibility and Plasmid Profiles of Staphylococcus aureus Strains Isolated from Bovine Subclinical Mastitis in Tabriz, Iran
ABSTRACT Background and Objectives: Mastitis caused by Staphylococcus aureus is a widely distributed disease in cattle, goats and sheep. The infection is often subclinical in cattle, leading to reduced milk production and quality, but acute catarrhal or even gangrenous inflammation may also occur. The aim of this study was to investigate resistance of S. au...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of pharmaceutical sciencesجلد ۶، شماره ۲، صفحات ۱۲۵-۱۳۲
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023